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PARADIGM-HF Trial design: Participants with NYHA class II-IV and LVEF ≤40%  were randomized to LCZ mg twice daily (n = 4,187) vs. enalapril 10 mg. -  ppt download
PARADIGM-HF Trial design: Participants with NYHA class II-IV and LVEF ≤40% were randomized to LCZ mg twice daily (n = 4,187) vs. enalapril 10 mg. - ppt download

Real-world effectiveness and safety of sacubitril/valsartan in heart failure:  A systematic review - International Journal of Cardiology
Real-world effectiveness and safety of sacubitril/valsartan in heart failure: A systematic review - International Journal of Cardiology

Emerging Mechanisms in the Management of Heart Failure With Reduced  Ejection Fraction
Emerging Mechanisms in the Management of Heart Failure With Reduced Ejection Fraction

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure | NEJM
Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure | NEJM

Update on PARADIGM-HF Prospective comparison of ARNI with ACEI to Determine  Impact on Global Mortality and morbidity in Heart Failure trial John J.V. -  ppt video online download
Update on PARADIGM-HF Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial John J.V. - ppt video online download

Sacubitril/Valsartan: Neprilysin Inhibition 5 Years After PARADIGM-HF |  JACC: Heart Failure
Sacubitril/Valsartan: Neprilysin Inhibition 5 Years After PARADIGM-HF | JACC: Heart Failure

Understanding the early mortality benefit observed in the PARADIGM-HF | VHRM
Understanding the early mortality benefit observed in the PARADIGM-HF | VHRM

Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart  Failure | Circulation
Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart Failure | Circulation

Clinical Trial and Biomarker Data | ENTRESTO® (sacubitril/valsartan) | HCP
Clinical Trial and Biomarker Data | ENTRESTO® (sacubitril/valsartan) | HCP

Neprilysin: Indications, Expectations, and Challenges | Revista Española de  Cardiología
Neprilysin: Indications, Expectations, and Challenges | Revista Española de Cardiología

Emerging Mechanisms in the Management of Heart Failure With Reduced  Ejection Fraction
Emerging Mechanisms in the Management of Heart Failure With Reduced Ejection Fraction

Entresto Use in Heart Failure w Preserved Function – The Early Career Voice
Entresto Use in Heart Failure w Preserved Function – The Early Career Voice

New heart failure agent doubles mortality benefit of ACE inhibitors -  PACE-CME
New heart failure agent doubles mortality benefit of ACE inhibitors - PACE-CME

Trial Scorecard: PARADIGM-HF
Trial Scorecard: PARADIGM-HF

PARADIGM-HF: A Concise Summary with Journal Club Questions - YouTube
PARADIGM-HF: A Concise Summary with Journal Club Questions - YouTube

Effect of sacubitril/valsartan versus enalapril on glycaemic control in  patients with heart failure and diabetes: a post-hoc analysis from the  PARADIGM-HF trial - The Lancet Diabetes & Endocrinology
Effect of sacubitril/valsartan versus enalapril on glycaemic control in patients with heart failure and diabetes: a post-hoc analysis from the PARADIGM-HF trial - The Lancet Diabetes & Endocrinology

PARADISE MI Trial: Is Sacubitril/valsartan (Entresto) useful in patients  with acute MI? – Visualmed
PARADISE MI Trial: Is Sacubitril/valsartan (Entresto) useful in patients with acute MI? – Visualmed

PDF] Critical Questions about PARADIGM-HF and the Future. | Semantic Scholar
PDF] Critical Questions about PARADIGM-HF and the Future. | Semantic Scholar

Sacubitril/Valsartan and Sudden Cardiac Death According to Implantable  Cardioverter-Defibrillator Use and Heart Failure Cause: A PARADIGM-HF  Analysis | JACC: Heart Failure
Sacubitril/Valsartan and Sudden Cardiac Death According to Implantable Cardioverter-Defibrillator Use and Heart Failure Cause: A PARADIGM-HF Analysis | JACC: Heart Failure

KoreaMed Synapse
KoreaMed Synapse

Differential Impact of Heart Failure With Reduced Ejection Fraction on Men  and Women - ScienceDirect
Differential Impact of Heart Failure With Reduced Ejection Fraction on Men and Women - ScienceDirect

Frontiers | Sacubitril/Valsartan as a Therapeutic Tool Across the Range of Heart  Failure Phenotypes and Ejection Fraction Spectrum
Frontiers | Sacubitril/Valsartan as a Therapeutic Tool Across the Range of Heart Failure Phenotypes and Ejection Fraction Spectrum

Use of Sacubitril/Valsartan in Heart Failure
Use of Sacubitril/Valsartan in Heart Failure

Industry Sponsored Trials and Entresto in CHF - REBEL EM - Emergency  Medicine Blog
Industry Sponsored Trials and Entresto in CHF - REBEL EM - Emergency Medicine Blog